Co-existing ossifying fibroma and pleomorphic adenoma in the head and neck region – a case report and review of the literature

Основное содержимое статьи

TO Aladelusi
OO Gbolahan
AO Fasola

Аннотация

Background: Presence of different cell lines in


the head and neck region allows for the rare


possibility of different neoplastic processes


occurring simultaneously. The occurrence of these


co-existing lesions could just be coincidental but


occasionally may be due to a local or systemic


cause. To the best of the authors’ knowledge, there


are no previous reports of co-existing ossifying


fibroma and pleomorphic adenoma in the head and


neck region in the English literature.


Case presentation: A 39-year old female


presented with a chief complaint of recurrent


swelling on the right side of the neck of nine years’


duration and left maxillary swelling of eight and a


half years duration both of which were spontaneous


in onset. The swellings had slowly increased in


size to the dimension at presentation with no other


significant findings in the medical and family


history. Following other relevant history,


examination and investigations a diagnosis of left


maxillary ossifying fibroma and right recurrent


parotid pleomorphic adenoma was made. Surgical


excision of the two lesions were done with good


outcome. We present a case of concurrent


ossifying fibroma and pleomorphic adenoma


occurring in the head and neck region. We also


discussed the most important features, biologic


behaviour and treatment of these two lesions and


reviewed the literature.


Conclusion: Although the co-existence of these


two lesions presented appear to be coincidental,


however, the possibility of an underlying systemic


link cannot be totally ruled out. Further reporting


of similar cases may help to throw more light for


better understanding of these multiple lesions.

Информация о статье

Раздел

Case Report

Библиографические ссылки

Cavaco BM, Barros L, Pannett AA, et al. The

hyperparathyroidism-jaw tumour syndrome in

Portuguese kindred. QJM. 2001 Apr;94(4):213-

doi: 10.1093/qjmed/94.4.213. PMID:

Akcam T, Altug HA, Karakoc O, et al.

Synchronous ossifying fibromas of the jaws: a

review. Oral Surg Oral Med Oral Pathol Oral

Radiol 2012;114 Suppl 5:120-125

Kaya Gª, Özalp Ö and Özbudak ÝH.

Synchronous occurrence of multiple distinct jaw

lesions in Simpson-Golabi-Behmel Syndrome: A

case report. Journal of Stomatology, Oral and

Maxillofacial Surgery. 2019;120(5):483-488. DOI:

1016/j.jormas.2018.12.001.

Khan SA, Sharma NK, Raj V and Sethi T.

Ossifying fibroma of maxilla in a male child: report

of a case and review of the literature. Natl J

Maxillofac Surg. 2011; 2(1): 73-79.

Levine P, Wiggins R, Archibald R and Britt R.

Ossifying fibroma of the head and neck:

Involvement of the temporal bone, an unusual

and challenging site. Laryngoscope 1981;91: 720-

Çakir B and Karadayi N. Ossifying fibroma in

the nasopharynx a case report. Clin Imaging.

;15: 290–292. DOI: 10.1016/0899-

(91)90122-C.

Thomas GK and Kasper KA. Ossifying fibroma

of the frontal bone. Arch Otolaryngol 1966; 83:

-46.

Mitrani M, Remsen K, Lawson W and Biller H.

Giant ossifying fibroma of the paranasal sinuses.

Ear Nose Throat J 1988; 67: 186-192

Gatt WM and Cronin JJ. Ossifying fibroma of

the sphenoid sinus. EENT Monthly 1975; 54: 67-

Margo C, Weiss A and Habal M. Psammomatioid

ossifying fibroma. Arch Ophthalmol

;104:1347-1351.

Bertolini F, Caradonna L, Bianchi B and Sesenna

E. Multiple ossifying fibroma of the jaws: a case

report. J Oral Maxillofac Surg. 2002; 60: 225–229.

Regezzi JA and Sciubba JJ. Oral Pathology. 3rd

ed. Philadelphia: W.B. Saunders; 1999. p. 357-

Neville BW, Damm DD, Allen CM and Bouquot

JE. Oral and maxillofacial pathology. 3rd ed.

Philadelphia: Saunders; 2009. p. 647.

Titinchi F and Morkel J. Ossifying fibroma:

analysis of treatment methods and recurrence

patterns. J Oral Maxillofac Surg. 2016; 74: 2409-

Rajendran S and Sivapathasundaram S. Shafer’s

textbook of oral pathology 6th ed. New Delhi,

Elsevier, 2009. p. 219224

Cawson RA and Odell EW. Cawson’s essentials

of oral pathology and oral medicine. 7th ed.

Edinburgh, Churchill Livingstone. 2008. p. 247-

Clark K. Etiology and familial inheritance of

pleomorphic adenomas Dentistry 3000. 2017;

(1). 4 pages. doi:10.5195/d3000.2017.70

Available from: https://www.researchgate.net/

p ub lica tion/ 31 75 94 60 8_ E tiology_ and

_familial_inheritance_of _pleomorphic_

adenomas [accessed Oct 02 2020].

Whatley WS, Thompson JW and Rao B. Salivary

gland tumours in survivors of childhood cancer.

Otolaryngol Head Neck Surg. 2006; 134(3): 385-

doi: 10.1016/j.otohns.2005.10.022. PMID:

Martinelli M, Martini F, Rinaldi E, et al.

Simian Virus 40 Sequences and expression of

the viral large T-antigen oncoprotein in Human

Pleomorphic Adenomas of Parotid Glands.

; 161(4): 1127–1133. PMID: PMC1867276

Sadetzki S, Chetrit A, Jarus-Hakak A, et al.

Cellular phone use and risk of benign and

malignant parotid gland tumors—a nationwide

case-control study. Am J Epidemiol.

;167(4):457-467. doi: 10.1093/aje/kwm325.

Epub 2007 Dec 6. PMID: 18063591.

Sunil S and Gopakumar D. Pleomorphic adenoma.

A case report and review of literature. Int. J.

Odontostomat. 2013; 7(2):171-174.

Naeim F. Forsberg MI. Waisman J and Coulson

WF. Mixed tumours of the salivary glands: growth

pattern and recurrence. Arch Pathol Lab Med.

; 100: 271–275

Dulguerov P, Todic J, Pusztaszeri M and

Alotaibi NH. Why Do Parotid Pleomorphic

Adenomas Recur? A Systematic Review of

Pathological and Surgical Variables. Front. Surg.

; 4:26. doi: 10.3389/fsurg.2017.00026

Andreasen S, Therkildsen MH, Bjorndal K and

Homoe P. Pleomorphic adenoma of the parotid

gland 1985-2010: a Danish nationwide study of

incidence, recurrence rate, and malignant

transformation. Head Neck. 2016; 38 Suppl 1:

E1364- E1369

Hua Yan, Kai Luo, BaoLong Liu and Jiamin Kang.

A solitary fibrous tumour with concurrent

meningioma at the same site: A case report and

review of the literature. Oncol Lett.

;11:3655–3659. doi: 10.3892/ol.2016.4486.

Murgod S, Girish HC, Savita JK and Varsha VK.

Concurrent central odontogenic fibroma and

dentigerous cyst in the maxilla: A rare case report.

J Oral Maxillofac Pathol. 2017; 21: 149–153.

Munde A, Modi P, Karle R, Wankhede P and

Shoeb S. Nonsyndromic Synchronous Multifocal

Central Giant Cell Granulomas of the

Maxillofacial Region: Report of a Case. Journal

of Dentistry (Tehran, Iran). 2015;12(2):157-162.

Haven CJ, Wong FK, van Dam EW, et al. A

genotypic and histopathological study of a large

Dutch kindred with hyperparathyroidism-jaw

tumour syndrome. J Clin Endocrinol Metab.

;85(4):1449-1454.

Yamashita Y, Akiyama T, Mizusawa N, Yoshimoto

K and Goto MA. A case of hyperparathyroidismjaw tumour syndrome found in the treatment of

an ossifying fibroma in the maxillary bone. Int J

Oral Maxillofac Surg. 2007;36:365–369.

Bradley ES and Leake D. Ossifying fibroma

involving the maxilla and mandible. Oral Surg Oral

Med Oral Pathol. 1968; 26: 605–614.

Yih W, Pederson GT and Bartley MH. Multiple

familial ossifying fibromas/ : Relationship to other

osseous lesions of the jaws. Oral Surg Oral Med

Oral Pathol. 1989; 68: 754–758.

Wang T, Zhang R, Wang L, et al. Two cases of

multiple ossifying fibromas in the jaws. Diagn

Pathol 2014; 9(1): 75. https://doi.org/10.1186/

-1596-9-75

Bernard EK, Akama MK and Vilembwa A.

Surgical management of aggressive synchronous

jaw central giant cell granuloma/ : case report.

East Afr Med J. 2012; 89: 282–284.

Horisk N, Stephenson E, Sayers C and Reid J.

Incidental finding of synchronous pleomorphic

salivary adenoma and Warthin’s tumour within a

TO Aladelusi, OO Gbolahan and AO Fasola

parotid gland. BMJ Case Rep. 2019; 12: e228675.

DOI: 10.1136/bcr-2018-228675.

Filippo R, Angelo P, Flavia O, et al. A Rare Case

of Synchronous Bilateral Pleomorphic Adenoma

of the Parotid Gland. Case Rep Clin Med. 2014;

: 387–391.

Siar CH and Ng K. Combined ameloblastoma

and odontogenic keratocyst’ or ‘keratinising

ameloblastoma. Br J Oral Maxillofac Surg

;31:183–186.

Fregnani ER, da Cruz Perez DE, Soares FA and

Alves FA. Synchronous ameloblastoma and

orthokeratinized odontogenic cyst of the mandible.

J Oral Pathol Med. 2006;35(9):573-575. doi:

1111/j.1600-0714.2006.00445.x. PMID:

Похожие статьи

Вы также можете начать расширеннвй поиск похожих статей для этой статьи.

Наиболее читаемые статьи этого автора (авторов)