Rezumat
Leiomyosarcomas of the uterus are highly malignant tumours that are rare and represent slightly over 1% of all uterine malignancies. The clinical presentation is fairly constant and includes abnormal vaginal bleeding, pains or both. Only two cases (0.6%) out of 337 uterine malignancies seen over a period of 15 years in Ile-Ife had histological diagnosis of leiomyosarcoma. Both patients were postmenopausal, aged 49 years and presented in advanced disease stage. Two months after surgery, one of the patients died from disease progression while the other defaulted while on chemotherapy. Leiomyosarcoma of the uterus though rare in our environment, when it occurs, presents with advanced stage of the disease. Poor compliance coupled with high cost of treatment portends poor prognosis thus making it rapidly fatal.
Keywords: Leiomyosarcoma, uterus, poor prognosis.
Résumé
Les léiomyosarcomes de l’utérus sont les tumeurs les plus contagieuses qui sont rare et représentent environ 1 % de tous les cas de tumeurs utérin. Les symptômes cliniques sont constants et inclus d’hémorragie vaginal anormale et des douleurs. Seulement 2 cas (0.6%) sur les 337 cas de tumeurs utérin étaient examinés histologiquement durant une période de 15 ans a Ilé Ifé. Les patients étaient à leur post ménopause, d’age moyenne de 39 ans et représentaient une étape avancée de lamaladie. Deux mois après la chirurgie, un des patients mourrait de la progression de la maladie alors que les autres sous traitement ne complétaient pas leur suivi. La léiomyosarcomes de l utérus bien que rare dans notre environnement parait à une étape avancée de la maladie. Le faible de conformité des patients joint au taux élevé des médicaments conduit à une prognosie faible rendant cette maladie fatale.
Correspondence: Dr. G.O. Omoniyi-Esan, Department of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria. Email: gomoniyi_esan@yahoo.com
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