Pathological characterization of colorectal polyps in Ilorin, Nigeria
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چکیده
Colorectal polyps especially the adenomas are recognized precursors of colorectal carcinoma. Identification and removal of such polyps before malignant transformation could reduce the burden of colorectal carcinoma. To document the demography and the histopathological types of colorectal polyps received by the Department of Pathology of University of Ilorin Teaching Hospital over a period of thirty years. This is a retrospective review of all cases of colorectal polyps that were received, processed and had histological diagnosis in our centre between 1979 and 2008 using the request cards and hematoxylin and eosin stained slides. Forty-four cases of colorectal polyps were reviewed constituting 6.7 percent of all colorectal biopsies/resections received in the same period. The male to female ratio was 2.1:1. Seventeen (38.6%) were adenomas, 9 (20.5%) were juvenile polyps, 8 (18.2%) were inflammatory polyps, 4 cases were lipomatous polyps, 3 were leiomatous polyps, and one each of lymphoid polyp, hamartomatous polyp and neurofibromatous polyp. Of the adenomas, 11 (58.8%) were tubular, 5 (29.4%) were villous, 1 (5.9%) was tubulovillous, and one was a villous adenoma with a focus of malignant transformation. Adenomatous polyp is the commonest pathological type of colorectal polyps in our centre. This study therefore sets out to review the age and sex distribution, location and morphological characteristics of all cases of colorectal polyps in our centre over the study period.
Keywords: Colorectal polyps, adenoma, colorectal cancer.
Résumé
Les tumeurs colorectales spécialement les adénomes sont reconnus comme précurseurs des carcinomes colorectaux. L’identification et la chirurgie de telles tumeurs avant leur transformation cancéreuse pourrait réduire la menace des carcinomes colorectaux. Pour documenter la démographie et les types d’histopathologie de tumeurs colorectaux reçu au département de pathologie du Centre Universitaire Hospitalier d’Ilorin depuis trois ans. Cette revue rétrospective de tous les cas reçu avec des analyses histologiques entre 1979 et 2008 utilisant les cartes de requête et les larmes teintées a hématoxyline et éosine. Quarante quatre cas de étaient revue et constitue 6.7 pour cent de tous les biopsies colorectaux pendant cette période. La proportion male et female était de 2.1:1. Dix sept (38.6%) étaient des adénomes, 9 (20.5%) étaient des tumeurs juvénile, 8 (18.2%) étaient des tumeurs inflammatoires, 4 cas étaient des tumeurs lépromateuses, 3 cas de tumeurs leiomateuses, et chaque cas de tumeurs lymphoidienne, hamartomatose et neurofibromatose. Des cas d’adénomes, 11 (58.8%) étaient tubulaires, 5 (29.4%) étaient villeuse, 1 (5.9%) tubulovilleux, et un cas d’adénomes villeux avec l’attention sur la transformation cancéreuse. Une tumeur adenomateuse est un type de pathologie commune de polype colorectal dans ce centre. Cette étude révèle la distribution en fonction d’âge et du sexe, site et les caractéristiques morphologiques de tous les cas de polypes colorectaux dans ce centre durant une période donnée.
Correspondence: Dr. OOK Ibrahim, Department of Pathology, College of Health Sciences, University of Ilorin, PMB 1515, Ilorin, Nigeria. E-mail: ookazeemibrahim@yahoo.co.uk
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