Parents’ Knowledge, Attitudes and Use of Antibiotics in Upper Respiratory Infections in Nigerian Children

Autor

  • C.C. Okide
  • O Grey-Ekejiuba
  • chukwuemeka M Ubaka
  • N Schellack
  • M Okonta

Słowa kluczowe:

Antibiotics, attitude, caregiver, children, misuse

Abstrakt

Parental knowledge of antibiotic use in upper respiratory tract infections (URTI) impacts significantly in the preservation of antibiotic efficacy, yet has not been adequately studied in Nigerian settings. This present study evaluated the knowledge, attitudes and self-medicating practices of caregivers towards the use of antibiotics in URTI among children.  The study was a cross-sectional and prospective survey. Parents visiting two hospitals (Nsukka General Hospital - rural and Enugu State University of Technology Teaching Hospital- urban) with their sick children (12 years and under) were approached to complete a 24-item questionnaire. The items assessed parental knowledge of, attitudes and self-medicating practices towards antibiotics in cases of URTI. Frequencies, means and inferential multivariate (chi-square, t-tests and regression) data analysis were conducted. The parents exhibited poor knowledge in most of the knowledge items. Younger parents, those visiting the urban hospital and those with higher educational status exhibited significantly better knowledge of antibiotics and URTI (p<0.05). The parents indicated marginally accepting attitudes towards antibiotics use and misuse and this was influenced largely by better antibiotic knowledge and better educational qualifications (p<0.001). However parents from both hospitals frequently self-medicated (88.6%) and acknowledged poor practices towards antibiotics such as the use of left over antibiotics. Majority (85%) of the parents also said they received antibiotics after they demanded it from their physicians. Parents in these study settings in Nigeria, possessed poor knowledge and positive attitudes of antibiotic use in their children, and exhibited poor practices when utilizing them

Bibliografia

Ahebwa A., Akol W., Achong E., Mugerwa T., Nakayenga A., Omega P., Rebecca N., Jacob S.I. (2017). Awareness of antimicrobial resistance among primary health workers in Buyende District, Rural Eastern Uganda. Microbiol. Res. J. Int. 22 (5), 1-11.

Centers for Disease Control and Prevention (2013). Antibiotic Resistance Threats in the United States. Available from: https://www.cdc.gov/drugresistance/threat-report-2013/index.html

Chang G.C., Tang S.F. (2006). Parental knowledge, attitudes and antibiotic use for acute upper respiratory tract infection in children attending a primary health clinic in Malyasia. Singapore Med. J. 47(4), 266-270.

Cole A. (2014). GPs feel pressurized to prescribe unnecessary antibiotics, survey finds. BMJ 2014; 349: g5238.

Davey P., Pagliari C., Hayes A. (2002). The patient’s role in the spread and control of bacterial resistance to antibiotics. Clin. Microbiol. Infect. 8 (Suppl 2), 43-68.

Dong LF, Yan H, Wang DL (2008). Antibiotic prescribing patterns in village health clinics across 10 provinces of Western China. J. Antimicrob. Chemother. 62(2), 410–415.

Dowell S.F., Schwartz B., Phillips W.R. (1998). Appropriate use of antibiotics for URI in children: Part II. Cough, pharyngitis and the common cold. The Pediatric URI Consensus Team. Am. Fam. Phys. 58(6), 1335-1345.

Ekwochi U., Chinawa J.M., Osuorah C.D., Odetunda O.I., Obu H.A., Agwu S (2014). The use of unprescribed antibiotics in management of upper respiratory tract infection in children in Enugu, South East, Nigeria. J. Trop. Pediatr. 60(3), 249-252.

Elan P., Katzenstein D., Frankish C.J., Herbert C.P., Milner R., Speert D., Chambers K. (2001). Prescribing practices and attitudes toward giving children antibiotics. Can. Fam. Phys. 47,521-527.

Fletcher-Lartey S., Yee M., Gaarslev C., Khan R. (2016) Why do general practitioners prescribe antibiotics for upper respiratory tract infections to meet patient expectations: a mixed methods study. BMJ Open 6(10), e012244.

Goff D.A., Bauer K.A., Reed E.E., Stevenson K.B., Taylor J.J., West J.E. (2012). Is the “low hanging fruit” worth picking for antimicrobial stewardship programs? Clin. Infect. Dis. 55, 587-592.

Goff D.A., File T.M. (2016). The evolving role of antimicrobial stewardship in management of multidrug resistant infections. Infect. Dis. Clin. N. Am. 30:539-551

Grigoryan L., Burgerhof J.G.M., Degener J.E., Deschepper R., Lundborg C.S., Monnet D.L., Scicluna E.A., Birkin J., Haaijer-Ruskamp F.M, SAR Consortium (2007). Attitudes, beliefs and knowledge concerning antibiotic use and self-medication: a comparative European study. Pharmacoepi. Drug. Saf. 16(11), 234–1243.

Hojsak I., Abdovic S., Szajewska H., Milosevic M., Krznaric Z., Kolacek S. (2010). Lactobacillus GG in the prevention of nosocomial gastrointestinal and respiratory tract infections. Pediatrics 15,e1171-1177.

Kurugol Z., Akilli M., Bayram N., Koturoglu G. (2006). The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children. Acta Paediatr. 95,1175-1181.

Merenstein D., Murphy M., Fokar A., Hernandez R.K., Park H., Nsouli H., Sanders M.E., Davis B.A., Niborski V., Tondu F., Shara N.M. (2010). Use of a fermented dairy probiotic drink containing Lactobacillus casei (DN-114 001) to decrease rate of illness in kids: the DRINK study. A patient-oriented, double blind, cluster-randomized, placebo-controlled, clinical trial. Eur. J. Clin. Nutr. 64, 669-677.

Molstad S., Erntell M., Hanberger H., Melander E., Norman C., Skoog G., Lundborg C.S., Soderstrom A., Torell E., Cars O. (2008). Sustained reduction of antibiotic use and low bacterial resistance: 10-year follow-up of the Swedish Strama programme. Lancet Infect. Dis. 8(2),125–132.

Nigeria Center for Disease Control (NCDC) (2017). National Action Plan for Antimicrobial Resistance 2017-2022. Federal Ministries of Agriculture, Environment and Health. Available from

https://ncdc.gov.ng/themes/common/docs/protocols/56_1510840387.pdf Accessed on August 13, 2019.

O’Neill J. (2014). Reviews on Antimicrobial resistance; Tackling a crisis for the health and wealth of nations. London; Review on Antimicrobial Resistance. Available from http://amr-review.org/Publications. Accessed on February 23, 2019

Panagakou S.G., Theodoridou M.N., Papaevangelou V., Papastergiou P., Syrogiannopoulos G.A., Goutziana G., Hadjichristodoulou C.S. (2009). Development and assessment of a questionnaire for a descriptive cross-section study concerning parents’ knowledge, attitudes and practices in antibiotic use in Greece. BMC Fam. Pract. 9:52.

Panagakou S.G., Spyridis N., Papaevangemou V., Theodoridou K.M., Goutziana G.P., Theodoridou M.N., Syrogiannopoulos A., Hadjichristodoulou C.S. (2011). Antibiotic use for upper respiratory tract infections in children: A cross-sectional survey of knowledge, attitudes and practices (KAP) of parents in Greece. BMC Pediatr. 11,60.

Parimi N., Pereira L.M., Prabhakar P. (2004). Caregivers’ practices, knowledge and beliefs of antibiotics in pediatric upper respiratory tract infections in Trinidad and Tobago: a cross sectional study. BMC Fam. Pract. 5, 28.

Pechère J.C. (2001). Patients’ Interviews and Misuse of Antibiotics. Clin. Infect. Dis. 33,S170-S173.

Sadoh W.E., Sadoh A.E., Ei-Udoko F.E. (2015). Parental contribution to over prescription of antibiotics for sore throat in children. Nig. J. Pediatr. 42(2), 98-102.

Satomura K., Kitamura T., Kawamura T., Shimbo T., Watanabe M., Kamei M., Tanako Y., Tamakoshi A., Great Cold Investigators (2005) Prevention of upper respiratory tract infections by gargling: a randomized trial. Am. J. Prev. Med. 9,302-307.

Simeons S. (2011). Factors affecting the cost effectiveness of antibiotics. Chemother. Res. Pract. 2011, 2011:Article 249867.

Stille C.J., Rifas-Shiman S.L., Kleinman K., Kotch J.B., Finkelstein J.A. (2008). Physician response to a community-level trail promoting judicious antibiotic use. Ann. Fam. Med. 6(3), 206-212.

Vakili R., Vahedian M., Khodaei G.H., Mahmoudi M. (2009). Effects of zinc supplementation in occurrence and duration of common cold in school aged children during cold season; a double-blind placebo-contolled trial. Iran J. Pediatr. 19,376-380.

World Health Organization. (2007). The world health report 2007. A safer future: global public health security in the 21st century.

World Health Organization (2015). Antibiotic Resistance: Multi-country Public Awareness Survey. Available from: http://www.who.int/drugresistance/documents/baselinesurveynov2015/en/ Assessed January 12, 2019.

Yu M., Zhao G., Lundborg S., Zhu Y., Zhao., Q, Xu B. (2014). Knowledge, attitudes and practices of parents in rural China on the use of antibiotics in children: a cross sectional study. BMC Infect. Dis.14,112

Opublikowane

2020-08-05

Numer

Dział

Original Articles

Jak cytować

Parents’ Knowledge, Attitudes and Use of Antibiotics in Upper Respiratory Infections in Nigerian Children. (2020). African Journal of Biomedical Research, 23(2), 213-220. https://ojshostng.com/index.php/ajbr/article/view/21

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