Dietary Intake and Nutrients Adequacy among Young Adults with Sickle Cell Disease in Ile-Ife, Southwest Nigeria

Authors

  • Florence Ifechukwude Aboderin
  • Patience Kehinde Alagbo
  • Glenda Mary Davison
  • Oluwafemi Omoniyi Oguntibeju

DOI:

https://doi.org/10.4314/ajbr.v27i1.6

Keywords:

Sickle cell disease, Anaemia, Dietary intake, Nutritional status, Haemoglobin

Abstract

Sickle cell disease (SCD) is a chronic and genetically mutated disease seen among the African descent, of which the need to study the nutritional status and the socio-demographic characteristics is a challenge. The aim of the study was to determine the dietary intake, level of nutritional status, and sociodemographic characteristics of people with sickle cell disease in Ile-Ife, Osun State, Nigeria. The study involved 100 participants, 50 in the test group (Hb SS patients) and 50 control (other genotypes/non-Hb SS patients) in the control group, recruited at the Obafemi Awolowo University’s health centre in Ile- Ife. A questionnaire was issued to gather information on participants.  Dietary data were obtained by the socio-demographic using 24-hour dietary recall, food frequency questionnaire was distributed to the participants. Characteristics, including their body mass index (BMS) height and weight were measured. From the study, about 76.3% of the respondents did not meet the total calorie needed while 23.7% met the expectation of total calorie needed daily. Proteins and carbohydrate as a major micronutrient met the requirement 54.6% and 93.8% respectively. Fibre intake was grossly inadequate with 80.4%, mineral salts and vitamins showed inadequate intake, most especially, folate, retinol, beta carotene and vitamin D. It is evident that nutritional management should go with medical care provided to patients with sickle cell disease. The nutritional management should also focus on conscious selection of food to ensure adequacy of both macronutrients and micronutrients necessary for maximum functioning of the body and maintaining good nutritional status.

References

ADERIBIGBE, A., OMOTOSO, A., AWOBUSUYI, J. & AKANDE, T. 1999. Arterial blood pressure in adult Nigerian sickle cell anaemia patients. West African journal of medicine, 18, 114-118.

AKODU, S. O., DIAKU-AKINWUMI, I. N. & NJOKANMA, O. F. 2012. Obesity—does it occur in Nigerian children with sickle cell anemia. Pediatric Hematology and Oncology, 29, 358-364.

AL-SAQLADI, A.-W., CIPOLOTTI, R., FIJNVANDRAAT, K. & BRABIN, B. 2008. Growth and nutritional status of children with homozygous sickle cell disease. Annals of tropical paediatrics, 28, 165-189.

BEHERA, S., DIXIT, S., BULLIYYA, G. & KAR, S. 2012. Vitamin A status and hematological values in sickle cell disorder cases. Indian Journal of Medical Sciences, 66, 169.

BELLO-MANGA, H., DEBAUN, M. R. & KASSIM, A. A. 2016. Epidemiology and treatment of relative anemia in children with sickle cell disease in sub-Saharan Africa. Expert review of hematology, 9, 1031-1042.

CHARLOTTE, E. E., RITHA CAROLE, M. B., CALIXTHE, I. P., JEANNE GEORGETTE, M. E., PATRICIA, E., IYAWA, H., EDGAR, M. M. L., MICHAEL NGENGE, B., GAELLE, N. K. & CLAUDIA, E. B. B. 2022. Describing the growth and nutritional status of sickle cell disease children and adolescents with reference to WHO growth standards in Cameroon. BMC nutrition, 8, 1-9.

CHAWLA, A., SPRINZ, P. G., WELCH, J., HEENEY, M., USMANI, N., PASHANKAR, F. & KAVANAGH, P. 2013. Weight status of children with sickle cell disease. Pediatrics, 131, e1168-e1173.

ESEZOBOR, C. I., AKINTAN, P., AKINSULIE, A., TEMIYE, E. & ADEYEMO, T. 2016. Wasting and stunting are still prevalent in children with sickle cell anaemia in Lagos, Nigeria. Italian Journal of pediatrics, 42, 1-8.

GLEW, R., CASADOS, J., HUANG, Y.-S., CHUANG, L.-T. & VANDERJAGT, D. 2003. Correlation of the fatty acid composition and fluid property of the cholesteryl esters in the serum of Nigerian children with sickle cell disease and healthy controls. Prostaglandins, leukotrienes and essential fatty acids, 68, 61-68.

HIBBERT, J. M., CREARY, M. S., GEE, B. E., BUCHANAN, I. D., QUARSHIE, A. & HSU, L. L. 2006. Erythropoiesis and myocardial energy requirements contribute to the hypermetabolism of childhood sickle cell anemia. Journal of pediatric gastroenterology and nutrition, 43, 680.

HIBBERT, J. M., FORRESTER, T. & JACKSON, A. A. 1992. Urea kinetics: comparison of oral and intravenous dose regimens. European journal of clinical nutrition, 46, 405-409.

HIBBERT, J. M., HSU, L. L., BHATHENA, S. J., IRUNE, I., SARFO, B., CREARY, M. S., GEE, B. E., MOHAMED, A. I., BUCHANAN, I. D. & AL-MAHMOUD, A. 2005. Proinflammatory cytokines and the hypermetabolism of children with sickle cell disease. Experimental Biology and Medicine, 230, 68-74.

HYACINTH, H., GEE, B. & HIBBERT, J. 2010. The role of nutrition in sickle cell disease. Nutrition and metabolic insights, 3, NMI. S5048.

MARTYRES, D. J., VIJENTHIRA, A., BARROWMAN, N., HARRIS‐JANZ, S., CHRETIEN, C. & KLAASSEN, R. J. 2016. Nutrient insufficiencies/deficiencies in children with sickle cell disease and its association with increased disease severity. Pediatric blood & cancer, 63, 1060-1064.

OKOLOSI, J. E. 2020. DIETARY PATTERN, NUTRITIONAL STATUS AND BLOOD PRESSURE LEVEL OF IN-SCHOOL ADOLESCENTS IN EDO STATE, NIGERIA.

ONUKWULI, V. O., CHINAWA, J., EKE, C. B., NWOKOCHA, A. R., EMODI, I. J. & IKEFUNA, A. N. 2018. Impact of zinc on sexual maturation of female sickle cell anemia (SCA) children in Enugu, Southeast Nigeria. Pediatric Hematology and Oncology, 35, 145-155.

OSEI-YEBOAH, C. & RODRIGUES, O. 2011. Renal status of children with sickle cell disease in Accra, Ghana. Ghana Medical Journal, 45.

PIEL, F. B., TATEM, A. J., HUANG, Z., GUPTA, S., WILLIAMS, T. N. & WEATHERALL, D. J. 2014. Global migration and the changing distribution of sickle haemoglobin: a quantitative study of temporal trends between 1960 and 2000. The Lancet Global Health, 2, e80-e89.

PLATT, O. S., ROSENSTOCK, W. & ESPELAND, M. A. 1984. Influence of sickle hemoglobinopathies on growth and development. New England Journal of Medicine, 311, 7-12.

PRASAD, A. S. 2002. Zinc deficiency in patients with sickle cell disease. Oxford University Press.

SINGER, T. G., BRAY, M. A., CHAN, A., IKEDA, S., WALTERS, B., FULLER, M. Y. & FALCO, C. 2020. Chronic Ulcers and Malnutrition in an African Patient. Pediatrics, 146.

STEPHEN, N., NDEN, N., GUSEN, N. J., KUMZHI, P. R., GAKNUNG, B., AUTA, D. A., BULNDI, L. B., MBURSA, C., KUMARI, V. P. & NANVYAT, N. 2018. Prevalence of sickle cell disease among children attending plateau specialist hospital, Jos, Nigeria.

TOLY-NDOUR, C., ROUQUETTE, A.-M., OBADIA, S., M’BAPPE, P., LIONNET, F., HAGEGE, I., BOUSSA-KHETTAB, F., TSHILOLO, L. & GIROT, R. 2011. High titers of autoantibodies in patients with sickle-cell disease. The Journal of rheumatology, 38, 302-309.

UKOHA, O., EMODI, I., IKEFUNA, A., OBIDIKE, E., IZUKA, M. & EKE, C. 2020. Comparative study of nutritional status of children and adolescents with sickle cell anemia in Enugu, Southeast Nigeria. Nigerian Journal of Clinical Practice, 23, 1079-1086.

UMEAKUNNE, K. & HIBBERT, J. M. 2019. Nutrition in sickle cell disease: recent insights. Nutrition and Dietary Supplements, 9-17.

VANDERJAGT, D., BONNETT, C., OKOLO, S. & GLEW, R. 2002. Assessment of the bone status of Nigerian children and adolescents with sickle cell disease using calcaneal ultrasound and serum markers of bone metabolism. Calcified tissue international, 71.

VANDERJAGT, D. J., OKOLO, S. N., RABASA, A. I. & GLEW, R. H. 2000. Bioelectrical impedance analysis of the body composition of Nigerian children with sickle cell disease. Journal of tropical pediatrics, 46, 67-72.

ZEMEL, B. S., KAWCHAK, D. A., FUNG, E. B., OHENE-FREMPONG, K. & STALLINGS, V. A. 2002. Effect of zinc supplementation on growth and body composition in children with sickle cell disease. The American journal of clinical nutrition, 75, 300-307.

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Published

2024-01-31

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Section

Original Articles

How to Cite

Dietary Intake and Nutrients Adequacy among Young Adults with Sickle Cell Disease in Ile-Ife, Southwest Nigeria. (2024). African Journal of Biomedical Research, 27(1), 49-54. https://doi.org/10.4314/ajbr.v27i1.6

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