An Assessment of tuberculosis intensified case finding and isoniazid preventive therapy for people living with HIV Nigeria
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Keywords

Tuberculosis, intensified case finding, isoniazid preventive therapy, people living with HIV, collaborative TB/HIV activities.

How to Cite

Abugu, L. I., Igbokwe, C. ., & Aji, J. (2020). An Assessment of tuberculosis intensified case finding and isoniazid preventive therapy for people living with HIV Nigeria. African Journal of Biomedical Research, 23(3), 367–373. Retrieved from https://ojshostng.com/index.php/ajbr/article/view/138

Abstract

Tuberculosis (TB) has remained the leading cause of morbidity and mortality among people living with HIV (PLHIV).  Nigeria has the highest incidence of TB/HIV co infection and HIV associated TB deaths in sub Saharan Africa. Therefore TB prevention among PLHIV is of utmost necessity. We assessed tuberculosis intensified case finding (ICF) cascade and isoniazid preventive therapy (IPT) for people living with HIV in heath care facilities in Enugu State, Nigeria. It was a cross sectional study conducted between February and May, 2019. We reviewed a total of 993 folders of PLHIV of PLHIV in the nine health care facilities offering ART in the State. Data was collected with ICF data collection form adapted from literature. Percentages were used to analyse data and their values compared using chi square statistics. Ninety eight point eight per cent of PLHIV had their TB screen done and documented as at last visit to the clinic, 80% of those screened positive had documented TB diagnostic evaluation while 96.2% of PLHIV with positive TB evaluation were placed on anti-TB treatment. Furthermore, 61.2 % of PLHIV had ever received a course of IPT. Significant differences were observed in TB screening by location and IPT administration by type of health care facility (p<.05).  Shortage of staff and poor remuneration were the most reported factors affecting implementation. The gaps identified in the implementation of ICF cascade and IPT have implications for public health and education. To reduce TB burden among PLHIV, all stakeholders must be involved in TB/HIV activities.

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References

REFERENCES

Abasie, A. and Yohanes, T. (2016): Assessemnt of isoniazid preventive therapy in the reduction of tuberculosis among ART patients in Arba Minch hospital, Ethiopia. Therapeutics and Clinical Risk Management, 13, 361-366. Doi https://doi.org/10.2147/TCRM.S127765

Alau, K.K., Weaver, M.R., Ogungbemi, M.K., Ashefer, G., Anenih, J., Adeyemi, A., et al. (2016): Prevalence of tuberculosis and HIV/AIDS co-infection among HIV clients at global fund supported comprehensive facilities in Nigeria. Int. Res. Med. Sci 4(6), 091-095. Available: http://www.apexjournal.org Accessed: 12th July 2017.

Arodiwe E.B., Nwokediuko, S.C., and Ike, S.O. (2014): Medical causes of death in a teaching hospital in South Eastern Nigeria: A 16 year review. Nigeria Journal of Clinical Practices, 17(6) 711-716. Doi: 10.4103/1119-3077.144383.

Bruchfield, J., Correia-Neves, M., and Kallenius, G. (2015): Tuberculosis and HIV Co-infection. Cold Spring Habour Perspectives in Medicine,5. Doi 10.1101/cshperspect.a017871

Cohen, L., Manion, L., and Morrison, K. (2011): Research methods in education (7th ed.). New York: Routledge Taylor & Francis Group, page 104.

Daniel, O.J., Adejumo, O.A., and Abdulrrazzaq (2015): Implementation of the Revised Guideline on TB/HIV Collaborative Activities in Lagos, Nigeria. IJTDH, 9(4),1-7.

Denegetu, A.W., and Dolamo, B.L. (2014) Tuberculosis case finding and isoniazid preventive therapy among people living with HIV at public health facilities of Addis Ababa, Ethiopia: a cross-sectional facility based study. BMC Public Health, 14:52. Available: http://www.biomedcentral.com/1471-2458/14/52 Accessed: 4th May, 2018.

Enugu State Vision 4:2020 (2010): The 1st ENV 4:2020 Medium Term Implementation Plan (EVMTIP) 2010-2013. An Economic Blue Print. Enugu State Government. Available: enugustate.gov.ng>2017/03pdf Last accessed: 13th February, 2020.

Galeto, A., Abate, D., and Egata, G. (2017): Intensified tuberculosis case finding, implementation of isoniazide preventive therapy and associated factors among people living with human immune-deficiency virus at Public health facilities of Harari Region, Eastern Ethiopia: A cross sectional study. International journal of health sciences, 11(1), 35-42.

Government of India (2016): Operational Manual for Isoniazid Preventive Therapy. Ministry of Health and Family welfare. National AIDS control Organization. New Delhi.

Kanabus, A. (2017): “Information about tuberculosis” GHE. Available: www.tbfacts.org Last accessed: 12th February, 2020.

Kassa, A., Jerene, D., Assefa, Y., Teka, A., Aseffa, A., and Deribew, A. (2012): Evaluation of collaborative TB/HIV activities in a general hospital in Addis Ababa, Ethiopia. BMC Res Notes, 5(67). Doi 10.1186/1756-0500-67

Kuyinu, Y.A, Mohammed, A.S., Adeyeye, O.O., Odugbemi, B.A., Goodman, O.O., and Odusanya, O.O. (2016): Tuberculosis infection control measures in health care facilities offering TB services in Ikeja Local government area, Lagos State, South West, Nigeria. BMC infectious diseases, 16:126. doi 10.1186/S12879-016-143-J.

Linguissi, L.S.G., Gwom, L.C., Nkenfou, C.N., Bates, M., Petersen, E., Zumla, A., and Ntoumi, F. (2017): Health systems in the Republic of Congo: challenges and opportunities for implementing tuberculosis and HIV collaborative service, research, and training activities. International Journal of Infectious Diseases 56, 62–67. Available from www.elsevier.com/locate/ijid

Nansera, D., Bajunirwe, F., Kabakyenga, J., Asiimwe, P.K.J., and Mayanja-Kizza, H. (2010): Opportunities and barriers for implementation of integrated TB and HIV care in lower level health units: experiences from a rural western Ugandan district. African Health Sciences, 10(4), 312 – 319.

National Strategic Plan for Tuberculosis Control (NSP-TB) (2015-2020): Towards Universal Access to Prevention Diagnosis and Treatment. National Tuberculosis and Leprosy Cotrol Programme, Department of Public Health, Federal Ministry of Health, Nigeria.

Nigeria Tuberculosis Profile (2017): Retrieved from www.who.int/tb/data. Accessed 10th July, 2017.

Okello, D. (2016): Assessment of the implementation of intensified tuberculosis case finding among HIV positive clients attending Kampala Capital City Authority public health facilities in Uganda. A thesis submitted in partial fulfillment of the requirements for the award of the Masters of Science Degree in Health Services Research of Makerere University. Makarere University Institution Repository. Retrieved from http://hdl.handle.net/10570/5612

Pasipamire, M., Pathmanathan, I., Calnan, M., Simelane, B., Trong T. A., and Haumba, S. (2016): Evaluation of TB/HIV collaborative activities in Swaziland: Intensified case finding Cascade, Provisions of Antiretroviral Therapy for HIV-Positive TB patients and TB infection control. Research and Evaluation Report USAID ASSIST Project. Bethesda, MD: University Research CD, UC (URC). Available: evaluation_of_tbhiv_swaziland_may_2016_ada.pdf Accessed: 23 July, 2017.

Sah, S.K., Sahu, S.K., Lamichhane, B., Bhatta, G.K., Bhandari, K.B., Owiti, P., and Majumdar, S.S. (2016): Dotting the Three I’s for collaborative TB-HIV activities: evaluation of a pilot programme in Kathmandu, Nepal. International Union Against Tuberculosis and Lung Disease Health solutions for the poor, 6 (3), 169–175. Doi: http://dx.doi.org/10.5588/pha.16.0012

Takarinda, K.C., Choto, R.C., Harries, A.D., Mutasa-Apollo, T., and Chakanyuka-Musanhu, C. (2017): Routine implementation of isoniazid preventive therapy in HIV-infected patients in seven pilot sites in Zimbabwe. International Union Against Tuberculosis and Lung Disease Health Solutions for the Poor, 7(1), 55–60

World Health Organisation, WHO (2011): Guidelines for intensified tuberculosis case-finding and isoniazid preventive therapy for people living with HIV in resource constrained settings. Geneva, World Health Organization.

World Health Organization (2012): WHO policy on collaborative TB/HIV activities. Guidelines for National programmes and other stakeholders. WHO.

World Health Organization (2016): Global Tuberculosis Report. Geneva, Switzerland. WHO. Available: https://www.who.int>global_report s23098en.pdf. Last accessed: 12th February, 2020.

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