Abstract
This study describes the duration of antibodies induced by intranasal PPRV vaccination using Boswellia Carteri gum in small ruminants. Ninety animals (45 goats and 45 sheep) were selected from three different pastoral herds (30 animals each) in Mudug region, Somalia. Group I had intranasal vaccination with B carteri gum, group II had subcutaneous route of vaccination and groups III and IV were gum alone and unvaccinated groups respectively. Serum samples collected from all animals at days 14, 28, 42, 56, 70, 84, 98, 128, 158, 188, 218, 248 and 278 of post vaccination to evaluate antibodies to PPRV vaccine using H-based blocking ELISA. The antibodies rose steadily after immunization in the sheep and goats, and a peak was noted in those vaccinated subcutaneously with an average PI of 68.9+4.4 and 66.7+5.8 respectively, followed by goats and sheep administered B carteri-PPR vaccine combination intranasal with an average PI of 67.47+4.3 and 65.4+5.8 respectively. The combined intranasal vaccination of PPRV and Boswellia is a potential non-invasive approach, if properly harnessed, can mitigate the recurrent economic losses from PPR since the antibodies could last more than 278 days.