How to Cite
Abstract
Many physiological factors such as ethnicity, sex and blood group have been proven to have roles to play in determining the bleeding and clotting time of an individual. Earlier studies had conflicting results about the bleeding and clotting time in an individual concerning physiological factors. The objective of the study was to study the bleeding and clotting time of an individual with respect to their sex and blood group. This cross-sectional study involved 134 undergraduate students between the ages of 17-25years. Blood group was determined using a standard anti-sera, clotting time was determined using the capillary method while the bleeding time was determined using Duke’s filter paper method. In this study, blood group B was predominate. The bleeding time and clotting time were significantly longer in females compared to that of males. The clotting time was longer in individuals with blood group O but the bleeding time among the blood groups was not significantly different. However, the subject size needs to be increased in further studies.
References
Abhishekh B, Mayadevi S, Meena D, Usha KC. (2011). Distribution of ABO and Rhesus-D blood groups in and around Thiruvananthapuram. Kerala Med J.1:28–9.
Ahmed O.A., Agomo P.U., Olukoya D.K., Esan G.J. (1993). The prevalence of ABO blood group antigens and antibodies in Lagos State, Nigeria. Afr J Med Med Sci. 22(3):49-53
Ambreen A, Muqeet W. (2016). Correlation of blood groups, bleeding time and clotting time in male and female students; An observational study. Pak J Pharm Res. 2:121-6.
Baishya R, Sarkar R, Barman B. (2017). Blood group and its relationship with bleeding time and clotting time- an observational study among the 1st MBBS students of Gauhati medical college, Guwahati. Int J Res Med Sci. 5:4147-50.
Chima O.K., Mohammed T.B., Aisha K.G., Alhaji S.A., Muhammad B.M., Kwaru A.H. (2012). ABO and rhesus blood groups among blood donors in Kano, North-Western Nigeria. Niger J Basic Clin Sci 2012;9:11-3
Daniel, M., M.C. Jaberoo, R.E. Stead, V.M. Reddy and A.A. Moir, (2006). Is admission for epistaxis more common in Caucasian than in Asian people? Preliminary study. Clin. Otolaryngol., 31: 386-389.
Egesie U. G., Egesie O. J, Usar I. and Johnbull T. O. (2008). Distribution Of Abo, Rhesus Blood Groups And Haemoglobin Electrophoresis Among The Undergraduate Students Of Niger Delta University Nigeria Nigerian Journal Of Physiological Sciences, Vol. 23, No. 1-2, pp. 5-8
Favaloro, E.J., S. Soltani, J. McDonald, E. Grezchnik, L. Easton and J.W.(2005).
Reassesment of ABO blood group, sex and age on laboratory parameters used to diagnose VonWillebrand disorder: Potential influence on the diagnosis Vs the potential association with risk of thrombosis. Am. J. Clin. Pathol., 124: 910-917.
Franchini M, Franco C., Giovanni T., Martina M., Giuseppe L.(2007). Relationship between ABO blood group and von Willebrand factor levels: from biology to clinical implications. Thromb J. 5:14.
Ghai, C.L., (1999). A Textbook of Practical Physiology. 5th Edn., Jaypee Brothers, New Delhi,Haematology, pp: 84-101.
Kaur M, Singh A, Bassi R, Kaur D. (2015). Blood group distribution and its relationship with bleeding time and clotting time. Natl J Physiol Pharm Pharmacol. 5:253-257.
Landsteiner K. (1900). Zur Kenntnis der antifermentativen lytischen and agglutinierenden Wirkung des Blutserums and der lymph. Zentralbl. Bakteriol. Parasit. Infekt. ;27:357–362.
Landsteiner K. U. (1900). Agglutinationserscheinungen normalen menschlichen Blutes. Wien. Klin. Wochenschr. 1901;14:1132–1134.
Mahapatra B. and Mishra N. (2009). Comparison of Bleeding Time and Clotting Time in
Different Blood Groups. American Journal of Infectious Diseases 5 (2): 106-108, 2009
Meena M and Sunil K.J. (2016). Distribution of blood group and its relation to bleeding time and clotting time. Int J Med Sci Public Health. 5:1-4
Miller V.M, Jayachandran M, Hashimoto K, Heit JA and Owen WG. (2008). Estrogen, inflammation and platelet phenotype. Gend Med. 5 Suppl A: S91-102
Patil SV, Gaikwad PB, Vaidya SR, Patil US, Kittad SD. (2013). To study the blood group distribution and its relationship with bleeding and clotting time in dental students. Asian J Medical Pharmaceutical Sci. 1(1):1–4.
Reddy V.M., Daniel M., Bright E., Broad S.R.and Moir A.A. (2008). Is there an association between blood group O and epistaxis? J Laryngol Otol. 122(4):366–8.
Reeta B. (2017). Blood group and its relationship with bleeding time and clotting time–an observational study among the 1st MBBS students of Gauhati medical college. Int J Res Med Sci. 5:4147-50.
Roy B Banerjee, Sathian B, Mondal M, Saha CG. (2011). Blood group distribution and its relationship with bleeding time and clotting time:a medical school based observational study among Nepali. Indian and Sri Lankan students. Nepal J Epidemiol. 1(4):135–40.
Sasekala.M and Saikumar P. (2013). Relationship Between Bleeding Time And Clotting Time Among Gender Difference And Varying Blood Groups In UG Medical Students . Volume 10, Issue 6 PP 40-43
Talib HV. (1991). Handbook of Medical Laboratory Technology, 2nd edn.New Delhi: CSB Publishers, 205–210.
Yasmeen N., ALI I. and Shaikh R. (2014). Gender-Based Blood Group Distribution and Its Relationship With Bleeding Time And Clotting Time In Medical Students. Biomedical & Pharmacology Journal Vol. 7(2), 619-621
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2020 Nigerian Journal of Physiological Sciences