Assessment of the lipid profile levels of lead acid battery factory worker occupationally exposed to heavy metals in Nnewi, Nigeria
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Анотація
Background of study:Cardiovascular disease (CVD)
and environmental degradation are leading global
health problems of our time. Recent studies have
linked exposure to heavy metals to the risks of CVD
and diabetes especially in populations of developing
countries like Nigeria. Materials and methods: This
is a cross-sectional study designed to assess the lipid
profile levels of lead acid battery factory workers
occupationally exposed to heavy metals in Nnewi,
Nigeria. A total of one hundred and seventeen (117)
participants comprised of control N (n=39), control
E (n=40) and lead acid battery factory workers
(V=38) aged between 18 and 56 years were recruited
for the study. 5ml of venous blood sample was
collected from each individual for the evaluation of
Triglyceride (TAG), Total cholesterol (TChol), Low
density lipoprotein cholesterol (LDL-C), High
density lipoprotein cholesterol (HDL-C) and Very
low density lipoprotein cholesterol (VLDL-C) levels
using standard laboratory methods.
Results: This showed thatTAG level for lead acid
battery factory workers (1.17±0.06) were
significantly reduced (p<0.05) compared with
control E (1.83±0.01) participants. Tchol and LDL
C levels were significantly elevated while VLDL-C
level was significantly reduced (p<0.05) in factory
workers when compared with control participants
(p<0.05) respectively. While the HDL-C level of lead
acid battery factory workers was elevated (p<0.05)
compared with control N (1.68 ±0.08 Vs 1.40±0.07;
p<0.05) participants, it was however, significantly
reduced compared with control E participants
(1.27±0.11Vs 2.40±0.02; p<0.05).
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Розділ
Посилання
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