Knowledge, perceptions, and attitude of nursing students on human papillomavirus infection and vaccine in Nigeria: a mixed methods design

Main Article Content

O Lawal
O Akpoghene-Adaiah
O Afolaranmi
O Arowojolu
O Opeyemi
YO Kareem
A Badejo
F Kowe
J Igwe
T Egbeyemi
M Savage
P Arinzechi
G Nwachukwu
D Obisesan
O Omoniyi
I Morhason-Bello

Abstract

Objective: Human papillomavirus (HPV)


vaccination is an efficient primary prevention of HPV


infections and associated lesions. Nursing trainees


are expected to be knowledgeable on public health


related diseases and preventive methods including


HPV vaccination. This study assessed knowledge


and attitude about HPV vaccination in Nigeria among


Nursing students in Ibadan.


Methods: It was a mixed methods study that involved


- two focus group discussions (FGD) and a cross


sectional survey among nursing students in two


institutions in Ibadan Nigeria. FGD data were


analysed using thematic content analysis technique.


A Spearman rank-order correlation and Kruskal


Wallis were used to test association between the


knowledge score of HPV infection and vaccine and


participant characteristics. Statistical analyses were


performed with STATA 15.0 software.


Results: The median age of students was 19 (IQR


20-21) years. In the FGDs, participants had good


knowledge of HPV infection, but little or no


knowledge about HPV vaccines. Only two


participants knew the correct name and dosages of


the available HPV vaccines. The median knowledge


score about HPV vaccine was 6 (4-8) and 53% of


the participant had a score >50% (6 and above). There


was strong evidence that age of participants and level


of year in the nursing school were associated with


good knowledge of HPV infection and vaccine


(p<0.05).


Conclusion: The knowledge of HPV infection,


related morbidities and vaccine was poor in this study.


We recommend increase in awareness of cervical


cancer including primary prevention of HPV infection


through vaccination. We also recommend early


introduction of HPV and related morbidities in nursing


curriculum as a subject to improve their knowledge


and better prepare them for public health intervention


role in the community.

Article Details

Section

Original Articles

References

Arbyn M, Weiderpass E, Bruni L, et al. Estimates

of incidence and mortality of cervical cancer in

: a worldwide analysis. Lancet Glob Health.

;8(2):e191-e203.

Mboumba Bouassa RS, Prazuck T, Lethu T, et

al. Cervical cancer in sub-Saharan Africa: a

preventable noncommunicable disease. Expert

Rev Anti Infect Ther. 2017;15(6):613-627.

Denny LA, Sankaranarayanan R, De Vuyst H,

et al. Recommendations for cervical cancer

prevention in sub-saharan Africa. Vaccine.

;31 Suppl 5:F73-4.

Okolo C, Franceschi S, Adewole I, et al. Human

papillomavirus infection in women with and

without cervical cancer in Ibadan, Nigeria. Infect

Agent Cancer. 2010;5(1):24.

Anorlu RI, Orakwue CO, Oyeneyin L and Abudu

OO. Late presentation of patients with cervical

cancer to a tertiary hospital in Lagos: what is

responsible? Eur J Gynaecol Oncol.

;25(6):729-732.

de Sanjose S, Brotons M and Pavon MA. The

natural history of human papillomavirus infection.

Best Pract Res Clin Obstet Gynaecol. 2018;47:2-

Arrossi S, Temin S, Garland S, et al. Primary

Prevention of Cervical Cancer: American Society

of Clinical Oncology Resource-Stratified

Guideline. J Glob Oncol. 2017;3(5):611-634.

Morhason-Bello IO, Wallis S, Adedokun BO and

Adewole IF. Willingness of reproductive-aged

women in a Nigerian community to accept human

papillomavirus vaccination for their children. J

Obstet Gynaecol Res. 2015;41(10):1621-1629.

Oluwole EO, Idowu OM, Adejimi AA, Balogun

MR,and Osanyin GE. Knowledge, attitude and

uptake of human papillomavirus vaccination

among female undergraduates in Lagos State,

Nigeria. J Family Med Prim Care.

;8(11):3627-3633.

Di JL, Rutherford S, Wu JL, et al. Knowledge

of Cervical Cancer Screening among Health

Care Workers Providing Services Across

Different Socio-economic Regions of China.

Asian Pac J Cancer Prev. 2016;17(6):2965-2972.

Olikoye RK. Nurses are essential to primary

health care. New Era Nurs Image Int. 1988;5:20.

Mahler H. Health care for all through primary

health care: nurses lead the way. New Era Nurs

Image Int. 1988;5:21-22.

Makwe CC and Anorlu RI. Knowledge of and

attitude toward human papillomavirus infection

and vaccines among female nurses at a tertiary

hospital in Nigeria. Int J Womens Health.

;3:313-7.

Pelullo CP, Esposito MR and Di Giuseppe G.

Human Papillomavirus Infection and Vaccination:

Knowledge and Attitudes among Nursing

Students in Italy. International journal of

environmental research and public health.

;16(10):1770.

Shetty S, Prabhu S, Shetty V and Shetty AK.

Knowledge, attitudes and factors associated with

acceptability of human papillomavirus vaccination

among undergraduate medical, dental and nursing

students in South India. Human Vaccines &

Immunotherapeutics. 2019;15(7-8):1656-65.

Sherman SM, Bartholomew K, Denison HJ, et

al. Knowledge, attitudes and awareness of the

human papillomavirus among health professionals

in New Zealand. PLoS One.

;13(12):e0197648.

Azuogu BN, Umeokonkwo CD, Azuogu VC, et

al. Appraisal of willingness to vaccinate

daughters with human papilloma virus vaccine

and cervical cancer screening uptake among

mothers of adolescent students in Abakaliki,

Nigeria. Niger J Clin Pract. 2019;22(9):1286-91.

Ogochukwu TN, Akabueze J., Ezeome .IV., et

al. . Vaccination against Human Papilloma Virus

in Adolescent Girls: Mother’s Knowledge,

Attitude, Desire and Practice in Nigeria. . JInfect

Dis Prev Med. 2017;5:151. doi:10.4172/2329-

1000151.

Villanueva S, Mosteiro-Miguens DG, DominguezMartis EM, Lopez-Ares D and Novio S.

Knowledge, Attitudes, and Intentions towards

Human Papillomavirus Vaccination among

Nursing Students in Spain. Int J Environ Res

Public Health. 2019;16(22).

Similar Articles

You may also start an advanced similarity search for this article.